mapkinase signaling pathway
| PAG Title | mapkinase signaling pathway |
| PAG ID | WAG000415 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | The ever evolving mitogen-activated protein kise (MAP kise) pathways consist of four major groupings and numerous related proteins which constitute interrelated sigl transduction cascades activated by stimuli such as growth factors, stress, cytokines and inflammation. The four major groupings are the Erk (red), JNK or SAPK (blue), p38 (green) and the Big MAPK or ERK5 (light blue) cascades. Sigls from cell surface receptors such as GPCRs and growth factor receptors are transduced, directly or via small G proteins such as ras and rac, to multiple tiers of protein kises that amplify these sigls and/or regulate each other. |
| Species | Homo sapiens |
| nCoCo Score | 2,652 |
| Base PAG ID | WAG000415 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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